The racetrack itself is as of 2015 now called The Downs At Mohegan Sun Pocono.

Mohegan Sun acquired the Pocono Downs racetrack on January 25, 2005 in a $280 million purchase of the Pocono Downs Racetrack from Penn National Gaming. Mohegan Sun renamed the property "Mohegan Sun at Pocono Downs," and began a major expansion. It began operation in November 2006 as the first slots casino in the state of Pennsylvania.

In January 2010, then Governor Ed Rendell signed a bill to legalize table games in Pennsylvania. The Mohegan Sun casino was among the first to receive approval for table games, and planned to hire 600 new employees for the expansion. Table games began operation on July 13, 2010.

In November 2013, Mohegan Sun opened a hotel that is connected to the casino floor.

On January 28, 2019, Mohegan Sun Pocono signed a partnership with Kindred Group to begin sports betting at a sportsbook at the casino along with offering online gambling and sports betting. Mohegan Sun Pocono became the first casino in Northeastern Pennsylvania to offer sports betting. On March 29, 2019, Mohegan Sun Pocono applied for a sports betting license; the license was approved on May 15, 2019. The casino constructed a 1,130 sq ft (105 m2) sportsbook that contains a video wall, 7 sports betting terminals, and 3 teller windows. The Unibet Sportsbook at Mohegan Sun Pocono opened on October 5, 2019, with former National Football League and Penn State linebacker LaVar Arrington in attendance for the ribbon-cutting ceremony. Unibet launched online gambling and online sports betting on November 12, 2019.

On March 18, 2020, Carmine Fusco, who trained and raced horses at The Downs at Poccono Downs, became the first resident of Pennsylvania to die from Coronavirus disease 2019.